Minoxidil Response Test

Finasteride Response Test

Assess the Effectiveness of Finasteride: Determine if it Works for You

Discover the pioneering and exclusive at-home pharmacogenetics test that revolutionizes how you address hair loss. 

Say goodbye to uncertainty and find a personalized solution that truly works for you.

Understanding Finasteride’s Mechanism of Action

  • Finasteride is a medication used to treat hair loss by inhibiting the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT).
  • DHT is implicated in the miniaturization of hair follicles and eventual hair loss, making finasteride an effective treatment option for androgenetic alopecia.

The Role of Androgen Receptor (AR) Gene

  • The androgen receptor (AR) gene plays a pivotal role in mediating the effects of DHT on hair follicles.
  • Variations in the AR gene, including the CAG repeat length, can influence androgen receptor sensitivity and, consequently, individual responses to finasteride therapy.

Significance of CAG Score in Finasteride Response

  • The CAG repeat polymorphism in the AR gene refers to the number of cytosine-adenine-guanine repeats in a specific region of the gene.
  • Studies have suggested that shorter CAG repeat lengths are associated with increased androgen receptor sensitivity, leading to a greater response to finasteride treatment.
  • Conversely, longer CAG repeat lengths may be associated with reduced androgen receptor sensitivity and a diminished response to finasteride therapy.

Predictive Value of CAG Score

  • By analyzing the CAG score as part of the Finasteride Response Test, clinicians can predict individual responses to finasteride therapy with greater accuracy.
  • Patients with shorter CAG repeat lengths may be more likely to experience positive outcomes with finasteride treatment, while those with longer CAG repeat lengths may require alternative treatment approaches.


The Finasteride Response Test offers a scientific approach to personalized hair loss treatment, leveraging the predictive power of the CAG score to optimize treatment outcomes. By understanding the genetic factors that influence individual responses to finasteride therapy, clinicians can tailor treatment plans to each patient’s unique genetic profile, maximizing efficacy and patient satisfaction.


1.Ganzer CA, Jacobs AR, Iqbal F. Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride: A Survey of Men Reporting Symptoms. Am J Mens Health. 2015;9(3):222-228.

2.Lee BH, Lee JS, Kim YW, Kim WI, Lee S, Kim SJ, Kim JY, Park JK, Hwang T. A novel missense mutation in the androgen receptor gene causes androgen insensitivity syndrome by inducing misfolding, structural disruption and aberrant splicing. J Biol Chem. 2020 Jul 24;295(30):10411-10423.

3.McCubrey JA, Lertpiriyapong K, Steelman LS, Abrams SL, Yang LV, Murata RM, Rosalen PL, Scalisi A, Neri LM, Cocco L, Ratti S, Martelli AM, Laidler P, Dulińska-Litewka J, Rakus D, Gizak A, Lombardi P, Nicoletti F, Candido S, Libra M, Montalto G, Cervello M. Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. Aging (Albany NY). 2017 Jul 3;9(6):1477-1536.

4.Yafi FA, Jenkins L, Albersen M, Corona G, Isidori AM, Goldfarb S, Maggi M, Nelson CJ, Parish S, Salonia A, Tan R, Mulhall JP; Androgen Deprivation Therapy Council of the Sexual Medicine Society of North America (SMSNA). Erectile Dysfunction. Nat Rev Dis Primers. 2016 May 26;2:16003.